BDBM50240612 CHEMBL306946::GNF-PF-2691::Indolo[2,1-b]quinazoline-6,12-dione::TCMDC-125859::TRYPTANTHRIN::US10669273, Compound 5a

SMILES O=C1c2ccccc2-n2c1nc1ccccc1c2=O

InChI Key InChIKey=VQQVWGVXDIPORV-UHFFFAOYSA-N

Data  3 KI  16 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240612   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataIC50:  150nMAssay Description:Inhibition of 5-lipooxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50240612(CHEMBL306946 | GNF-PF-2691 | Indolo[2,1-b]quinazol...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed